KMID : 1036320150370010035
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Maxillofacial Plastic and Reconstructive Surgery 2015 Volume.37 No. 1 p.35 ~ p.35
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Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study
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Park Si-Yeok
Park Young-Wook Ji Young-Jun Park Sung-Wook Kim Seong-Gon
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Abstract
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Background: The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model.
Methods: Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n?=?5) or 20 units (group 2, n?=?5).
Results: The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P?0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P?=?0.013).
Conclusion: Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection.
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KEYWORD
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Botulinum toxin type A, Electromyography, Masseter muscle, Peak voltage
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